GPR124 (ADGRA2) Rabbit Polyclonal Antibody

SKU TA351229

Rabbit Polyclonal Anti-GPR124 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Rat urinary bladder tissue lysate; IHC: 50-200; Positive control: Human liver cancer; Predicted cell location: Cell membrane
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GPR124
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 143 kDa
• Gene Name: adhesion G protein-coupled receptor A2
• Database Link:
  NP_116166
  Q96PE1
• Background: TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
• Synonyms: GPR124; TEM5

Reference Data

• Protein Families: Druggable Genome, Transmembrane