DHH Rabbit Polyclonal Antibody

CAT#: TA351138

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Rabbit Polyclonal Anti-DHH Antibody


 Product Datasheet for 'TA351138'

USD 335.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name Polyclonal
Applications IHC
Recommend Dilution ELISA: 2000-5000, IHC: 50-200
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human DHH
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration 3.4 mg/ml
Purification Antigen affinity purification
Gene Name desert hedgehog
Background This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Synonyms GDXYM; HHG-3; SRXY7
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease
Protein Pathways Hedgehog signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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ANTIBODY VALIDATION 101
BOGO Free lysates
68 Mouse Clones