CENPE Rabbit Polyclonal Antibody

CAT#: TA351071

Rabbit Polyclonal Anti-CENPE Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Human vermiform appendix tissue lysate Primary antibody: TA351071 (CENPE Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 40 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351071 (CENPE Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351071 (CENPE Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human vermiform appendix tissue lysate
  IHC: 50-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CENPE
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 316 kDa
• Gene Name: centromere protein E
• Database Link:
  NP_001804
  Entrez Gene 1062 Human
  UniProt ID Q02224
• Background: Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
• Synonyms: CENP-E; KIF10; MCPH13; PPP1R61

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency