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CCR6 Rabbit Polyclonal Antibody

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SKU
TA351040
Rabbit Polyclonal Anti-CCR6 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
In Stock*
Bulk/Customize

Frequently Bought Together (2)

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LY401394 Transient overexpression lysate of chemokine (C-C motif) receptor 6 (CCR6), transcript variant 1 (as WB positive control) 100 ug
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View other "CCR6 or NM_004367" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Human bladder transitional cell carcinoma grade 2-3 tissue, HepG2 cell, HT-29 cell, 231 cell lysates
IHC: 20-100
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human CCR6
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 42 kDa
Gene Name C-C motif chemokine receptor 6
Database Link
Background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Synonyms BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
Reference Data
Protein Categories Allergies and autoimmune diseases, CD Markers, Chemokines, GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
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Documents
Resources

file-alt Citations

Role and recruitment of Th9 cells in liver cirrhosis patients
Qin, Wang, Chen et al
Asian Pacific Journal of Tropical Biomedicine (2016)
AI Summary: OriGene's CCR6 primary antibody was used in this study to detect and analyze the expression of CCR6 in liver tissue samples from cirrhosis patients, contributing to the investigation of Th9 cell recruitment.
Snippet: Primary antibodies [chemokine receptor type 6 (CCR6;Origene, USA), chemokine ligand 20 (CCL20;Bioss, Beijing, China) and α-smooth muscle actin (SMA;Sigma-Aldrich, USA)] were added and then incubated overnight at 4 °C. After ... Cite SaveSaving
IHC
Showing 1-1 of 1 papers.
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