ARAP1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 100-300 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARAP1 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| Database Link | |
| Background | The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | CENTD2 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Endocytosis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic therapy
Nadaraja, Schledermann, Herrstedt et al
Acta Oncol (2019) 59 (1), 40-47 DOI: 10.1080/0284186X.2019.1657941
Nadaraja, Schledermann, Herrstedt et al
Acta Oncol (2019) 59 (1), 40-47 DOI: 10.1080/0284186X.2019.1657941
AI Summary: OriGene's rabbit polyclonal anti-ARAP1 antibody was used for immunohistochemistry to assess ARAP1 protein expression in tumor samples, contributing to the identification of ARAP1 as an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma.
Snippet: AbstractBackground: Little is known about the biological factors influencing ovarian cancer (OC) patient outcome, especially in older patients who are often underrepresented in clinical trials. We ...;Immunostaining was performed by incubating sections with rabbit polyclonal anti-ARAP1 antibody (1:1000 dilution;Origene, Rockville, MD, USA) in citrate buffer, pH 6.0, for 60 min
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
