SCAP Rabbit Polyclonal Antibody

SKU TA350390

Rabbit Polyclonal Anti-SCAP Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human esophagus cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SCAP
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: SREBF chaperone
• Database Link:
  NP_036367
  Q12770
• Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
• Synonyms: KIAA0199

Reference Data

• Protein Families: Druggable Genome, Transcription Factors, Transmembrane