PGRMC2 Rabbit Polyclonal Antibody

CAT#: TA350279

Rabbit Polyclonal Anti-PGRMC2 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-2: RAW264.7 and NIH/3T3 cell lysates Primary antibody: TA350279 (PGRMC2 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350279 (PGRMC2 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350279 (PGRMC2 Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA350279 (PGRMC2 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA350279 (PGRMC2 Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: RAW264.7 and NIH/3T3 cell lysates
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PGRMC2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: progesterone receptor membrane component 2
• Database Link:
  NP_006311
  Entrez Gene 70804 MouseEntrez Gene 361940 RatEntrez Gene 10424 Human
  UniProt ID O15173
• Background: PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction.
• Synonyms: DG6; PMBP

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transmembrane