Optimedin (OLFM3) Rabbit Polyclonal Antibody

SKU
TA350251
Rabbit Polyclonal Anti-OLFM3 rabbit polyclonal antibody
  $205.00
In Stock*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 200-1000
WB positive control: Mouse intestines tissue
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human OLFM3
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 55 kDa
Gene Name olfactomedin 3
Database Link
Background OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Synonyms NOE3; NOELIN3; OPTIMEDIN
Reference Data
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Secreted Protein
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