MT3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MT3 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | metallothionein 3 |
| Database Link | |
| Background | Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease. |
| Synonyms | GIF; GIFB; GRIF; ZnMT3 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
GPR17 Suppresses Triple-Negative Breast Cancer Progression and Serves as an Independent Prognostic Biomarke
Liu, Wei, Zhang et al
World J Surg Oncol (2026)
Liu, Wei, Zhang et al
World J Surg Oncol (2026)
AI Summary: OriGene’s anti-GPR17 antibody was used in this study to detect GPR17 protein expression via western blotting, enabling the authors to assess GPR17 levels in triple-negative breast cancer cells and tissues.
Snippet: Background: G protein-coupled receptor 17 (GPR17), a Gi protein-coupled receptor, has been defined poorly about its roles and clinical significance in triple-negative;Equal amounts of protein (30 μg per lane) were separated by 12% SDS-PAGE and transferred onto PVDF membranes (Millipore, #IPVH00010). …
Showing 1-1 of 1 papers.
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