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TAB3 Rabbit Polyclonal Antibody

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SKU
TA350153
Rabbit Polyclonal Anti-TAB3 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: 293T, Raw264.7, NIH/3T3, K562 and Jurkat cells
IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human TAB3
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 79 kDa
Gene Name TGF-beta activated kinase 1/MAP3K7 binding protein 3
Database Link
Background The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Synonyms MAP3K7IP3; NAP1
Reference Data
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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