P3H3 Rabbit Polyclonal Antibody

CAT#: TA350132

Rabbit Polyclonal Anti-LEPREL2 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-3: A549 cells mouse heart tissue Hela cells Primary antibody: TA350132 (P3H3 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human rectal cancer tissue using TA350132 (P3H3 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human rectal cancer tissue using TA350132 (P3H3 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human placenta tissue using TA350132 (P3H3 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human placenta tissue using TA350132 (P3H3 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A549 cells, mouse heart tissue and Hela cells
  IHC: 50-200
  Positive control: Human rectal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human LEPREL2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: prolyl 3-hydroxylase 3
• Database Link:
  NP_055077
  Entrez Gene 10536 Human
  UniProt ID Q8IVL6
• Background: The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
• Synonyms: GRCB; HSU47926; LEPREL2