FUCA1 Rabbit Polyclonal Antibody

CAT#: TA349998

Rabbit Polyclonal Anti-FUCA1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 60 μg Lane: Human placenta tissue Primary antibody: TA349998 (FUCA1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2minutes

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349998 (FUCA1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349998 (FUCA1 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349998 (FUCA1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349998 (FUCA1 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human placenta tissue
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FUCA1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: fucosidase, alpha-L- 1, tissue
• Database Link:
  NP_000138
  Entrez Gene 71665 MouseEntrez Gene 2517 Human
  UniProt ID P04066
• Background: The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
• Synonyms: FUCA

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Other glycan degradation