BMX Rabbit Polyclonal Antibody

SKU TA349946

Rabbit Polyclonal Anti-BMX Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human ovarian cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human BMX
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: BMX non-receptor tyrosine kinase
• Database Link:
  NP_001712
  P51813
• Background: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: ETK; PSCTK2; PSCTK3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase