CLPS Rabbit Polyclonal Antibody

SKU TA349812

Rabbit Polyclonal Anti-CLPS Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human esophagus cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CLPS
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: colipase
• Database Link:
  NP_001823
  P04118
• Background: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
• Synonyms: colipase; OTTHUMP00000016271; pancreatic; pancreatic colipase preproprotein

Reference Data

• Protein Families: Secreted Protein, Transmembrane