CCDC106 Rabbit Polyclonal Antibody

CAT#: TA349754

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Rabbit Polyclonal Anti-CCDC106 Antibody

USD 380.00

In Stock

    • 100 ul

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Product Data
Applications IHC
Recommended Dilution IHC: 100-300
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human CCDC106
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name coiled-coil domain containing 106
Background The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Synonyms HSU79303; ZNF581
Reference Data
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