C3AR1 Rabbit Polyclonal Antibody

CAT#: TA349727

Rabbit Polyclonal Anti-C3AR1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse brain tissue lysate Primary antibody: TA349727 (C3AR1 Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 40 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349727 (C3AR1 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349727 (C3AR1 Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue lysate
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human C3AR1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: complement component 3a receptor 1
• Database Link:
  NP_004045
  Entrez Gene 12267 MouseEntrez Gene 719 Human
  UniProt ID Q16581
• Background: The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptorprotein involved in the complement system. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
• Synonyms: AZ3B; C3AR; HNFAG09

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Complement and coagulation cascades, Neuroactive ligand-receptor interaction