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NEK2 Rabbit Polyclonal Antibody

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SKU
TA349610
Rabbit Polyclonal Anti-NEK2 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY419288 Transient overexpression lysate of NIMA (never in mitosis gene a)-related kinase 2 (NEK2) (as WB positive control) 100 ug
$436.00

View other "NEK2 or NM_002497" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 500-2000
WB positive control: Lovo cells
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human NEK2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 52 kDa
Gene Name NIMA related kinase 2
Database Link
Background This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
Synonyms HsPK21; NEK2A; NLK1; PPP1R111; RP67
Reference Data
Protein Categories Cytokines, Enzyme: Kinases, Intracellular Proteins, Nervous system Diseases
Protein Families Druggable Genome, Protein Kinase
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Documents
Resources

file-alt Citations

Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2
Zhao, Han, Liu et al
Thorac Cancer (2017)
AI Summary: In this study, the anti-NEK2 antibody (TA349610) from OriGene was used to detect NEK2 protein levels, helping to demonstrate that deguelin inhibits metastasis in non-small cell lung cancer cells by downregulating NEK2.
Snippet: The primary antibodies against E-cadherin (14472S), Vimentin (5741S) and GAPDH (5174S) were purchased from Cell Signaling Technology (Danvers, MA, USA), and anti-NEK2 antibody (TA349610) was obtained from OriGene (Rockville, MD, USA). ... All 2 versions Cite SaveSaving
WB
Showing 1-1 of 1 papers.
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