NRG4 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC |
---|---|
Recommended Dilution | IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NRG4 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | neuregulin 4 |
Database Link | |
Background | Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by theNRG4 gene. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. |
Synonyms | HRG4 |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | ErbB signaling pathway |
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