NGF Rabbit Polyclonal Antibody

SKU
TA349414
Rabbit Polyclonal Anti-NGF Antibody
  $205.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human NGF
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name nerve growth factor
Database Link
Background This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Synonyms Beta-NGF; HSAN5; NGFB
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system Diseases, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway
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Documents
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file-alt Citations

Targeting nNOS ameliorates the severe neuropathic pain due to chronic pancreatitis
Demir, Heinrich, Carty et al
EBioMedicine (2019) 46, 431-443 DOI: 10.1016/j.ebiom.2019.07.055
AI Summary: OriGene products contributed to this study by providing the nNOS (neuronal nitric oxide synthase) antibody (Rabbit Polyclonal, Cat# TA326306) and the BDNF (brain-derived neurotrophic factor) antibody (Mouse Monoclonal, Cat# TA502410), which were used for immunohistochemical analyses to investigate molecular mediators of neuropathic pain in chronic pancreatitis.
Snippet: ) BDNF Mouse Monoclonal 10 μg/ml (N) CalBiochem (San Diego, CA, USA) NT-3 Mouse Monoclonal 1 μg/ml (N) R&D systems, Germany NGF Rabbit Polyclonal 3 μg/ml (N) Acris Antibodies, Herford, Germany S100 Mouse Monoclonal 1:150 (IF) Merck Millipore, Darmstadt, Germany Recombinant protein  rhBDNF Human 10 ng/ml Sigma-Aldrich, St. Louis, M
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IF
Improvement in bladder dysfunction after bladder transplantation of amniotic fluid stem cells in diabetic rats
Liang, Shaw, Huang et al
Sci Rep (2018) 8 (1), 2105 DOI: 10.1038/s41598-018-20512-z
AI Summary: OriGene’s rabbit polyclonal antibody against NGF was used to detect nerve growth factor levels in bladder tissue, helping assess molecular changes after amniotic fluid stem cell transplantation in diabetic rats.
Snippet: After blocking with Dako REAL peroxidase blocking solution (code S2023, DAKO Corp, Carpinteria, CA) for 20 minutes, sections were washed and incubated for 18-20 hours at 4 °C with a rabbit polyclonal antibody directed against NGF (1:700, OriGene Technologies
FigureFigureFigure
Bladder Transplantation of Amniotic Fluid Stem Cell may Ameliorate Bladder Dysfunction After Focal Cerebral Ischemia in Rat
Liang, Shaw, Huang et al
Stem Cells Transl Med (2017) 6 (4), 1227-1236 DOI: 10.1002/sctm.16-0212
Cited by 24
AI Summary: In this study, OriGene's NGF (Cat# SR321060), CHRM2 (Cat# SR506434), CHRM3 (Cat# SR506435), and P2RX1 (Cat# SR506436) qPCR primer sets were used to measure gene expression changes in rat bladders, helping to assess the molecular effects of amniotic fluid stem cell transplantation after cerebral ischemia.
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Showing 1-3 of 3 papers.
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