NGF Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NGF |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | nerve growth factor |
| Database Link | |
| Background | This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
| Synonyms | Beta-NGF; HSAN5; NGFB |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system Diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Demir, Heinrich, Carty et al
EBioMedicine (2019) 46, 431-443 DOI: 10.1016/j.ebiom.2019.07.055
Liang, Shaw, Huang et al
Sci Rep (2018) 8 (1), 2105 DOI: 10.1038/s41598-018-20512-z
Liang, Shaw, Huang et al
Stem Cells Transl Med (2017) 6 (4), 1227-1236 DOI: 10.1002/sctm.16-0212
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