ncapd2 Rabbit Polyclonal Antibody

CAT#: TA349196

Rabbit Polyclonal Anti-RNF121 Antibody

Product Images

Western blot analysis of RNF121 in MCF7 cell lysate with RNF121 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RNF121 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RNF121.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: RNF121 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 24, 27, 36 kDa; Observed: 28 kDa
• Gene Name: non-SMC condensin I complex, subunit D2
• Database Link:
  NP_060790
  UniProt ID Q9H920
• Background: RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).
• Synonyms: FLJ11099