PACS2 Rabbit Polyclonal Antibody

CAT#: TA349176

Rabbit Polyclonal Anti-PACS2 Antibody

Product Images

Western blot analysis of PACS2 in mouse brain tissue lysate with PACS2 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: PACS2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 98 kDa; Observed: 95 kDa
• Gene Name: phosphofurin acidic cluster sorting protein 2
• Database Link:
  NP_056012
  Entrez Gene 23241 Human
  UniProt ID Q86VP3
• Background: PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).
• Synonyms: RNF155