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EPLIN (LIMA1) Rabbit Polyclonal Antibody

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SKU
TA349125
Rabbit Polyclonal Anti-LIMA1 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 0.5 - 1 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen LIMA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human LIMA1
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification LIMA1 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 50, 66, 84 kDa; Observed: 65 kDa
Gene Name LIM domain and actin binding 1
Database Link
Background The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines (1,2). LIMA1 is also a key molecule linking the cadherin-catenin complex to the actin cytoskeleton (3). Recent studies have shown that EGF activates ERK1/2-dependent phosphorylation, ubiquitination and degradation of LIMA1, leading to increased invasiveness and metastasis of metastatic prostate cancer models (4).
Synonyms MRT2; MRT2A
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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