RHOG Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | RHOG antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOG. |
Buffer | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | RHOG antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | Predicted: 21 kDa; Observed: 23 kDa |
Gene Name | ras homolog family member G |
Database Link | |
Background | The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3). |
Synonyms | ARHG |
Reference Data |
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