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MYO7B Rabbit Polyclonal Antibody

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SKU
TA349105
Rabbit Polyclonal Anti-Nephrin Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
5 Days*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Nephrin antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Nephrin.
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification Nephrin antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 125, 137 kDa; Observed: 125 kDa
Gene Name myosin VIIB
Database Link
Background Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth (1). Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm (2,3).
Synonyms DKFZp686A08248
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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