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XKR8 Rabbit Polyclonal Antibody

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SKU
TA349099
Rabbit Polyclonal Anti-XKR8 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen XKR8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human XKR8.
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification XKR8 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 43 kDa; Observed: 47 kDa
Gene Name XK related 8
Database Link
Background The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1). XKR8 is thought to be a ??cramblase?? an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2).
Synonyms hXkr8; XRG8
Reference Data
Protein Categories Membrane Proteins
Protein Families Transmembrane
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