XKR8 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | XKR8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human XKR8. |
| Buffer | PBS containing 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | XKR8 antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | Predicted: 43 kDa; Observed: 47 kDa |
| Gene Name | XK related 8 |
| Database Link | |
| Background | The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1). XKR8 is thought to be a ??cramblase?? an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2). |
| Synonyms | hXkr8; XRG8 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
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