POU2F3 Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3. |
Buffer | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | POU2F3 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | Predicted: 48 kDa; Observed: 55 kDa |
Gene Name | POU class 2 homeobox 3 |
Database Link | |
Background | POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4). |
Synonyms | Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a |
Reference Data |
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