RAN Rabbit Polyclonal Antibody

CAT#: TA347994

Rabbit Polyclonal Anti-RAN Antibody

Product Images

Western blot analysis of RAN expression in LOVO cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-RAN Antibody: A synthesized peptide derived from human RAN
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: RAN, member RAS oncogene family
• Database Link:
  NP_006316
  Entrez Gene 19384 MouseEntrez Gene 84509 RatEntrez Gene 5901 Human
  UniProt ID P62826
• Background: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
• Synonyms: ARA24; Gsp1; TC4
• Note: RAN Antibody detects endogenous levels of total RAN

Reference Data

• Protein Families: Druggable Genome, Transcription Factors