TWIST2 Rabbit Polyclonal Antibody

CAT#: TA347852

Rabbit Polyclonal Anti-Twist2 Antibody

Product Images

Western blot analysis of extracts from A549, Hela and 3T3 cells using Twist2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Twist2 Antibody: Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 18kd
• Gene Name: twist family bHLH transcription factor 2
• Database Link:
  NP_476527
  Entrez Gene 13345 MouseEntrez Gene 59327 RatEntrez Gene 117581 Human
  UniProt ID Q8WVJ9
• Background: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
• Synonyms: AMS; BBRSAY; bHLHa39; DERMO1; FFDD3; SETLSS
• Note: The antibody detects endogenous level of total Twist2 protein.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors