E2F2 Rabbit Polyclonal Antibody

CAT#: TA347847

Rabbit Polyclonal Anti-E2F-2 Antibody

Product Images

Western blot analysis of extracts from Hela and K562 cells using E2F-2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-E2F-2 Antibody: Peptide sequence around aa.425~429(L-F-D-S-Y) derived from Human E2F-2.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45kd
• Gene Name: E2F transcription factor 2
• Database Link:
  NP_004082
  Entrez Gene 242705 MouseEntrez Gene 1870 Human
  UniProt ID Q14209
• Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
• Synonyms: E2F-2
• Note: The antibody detects endogenous level of total E2F-2 protein.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer