FARP2 Rabbit Polyclonal Antibody

CAT#: TA347647

Rabbit Polyclonal Anti-FIR Antibody

 Product Datasheet for 'TA347647'

USD 335.00

3 Weeks

    • 100 ug

Product images


Product Data
Clone Name Polyclonal
Applications WB
Recommend Dilution WB: 1:500-1:2000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen for anti-FIR Antibody: A synthesized peptide derived from human FIR
Isotype IgG
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration 1 mg/ml
Purification Immunogen affinity purified
Predicted Protein Size 119 kDa
Gene Name FERM, ARH/RhoGEF and pleckstrin domain protein 2
Background Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor.Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding. 2 isoforms of the human protein are produced by alternative splicing.
Synonyms FIR; FRG; PLEKHC3
Note FIR Antibody detects endogenous levels of FIR
Reference Data
Protein Pathways Adherens junction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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