TRADD Rabbit Polyclonal Antibody

CAT#: TA347499

Rabbit Polyclonal Anti-TRADD Antibody

Product Images

Western blot analysis on COS7 and HuvEc cell lysate using TRADD Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TRADD Antibody: A synthesized peptide derived from human TRADD
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: TNFRSF1A associated via death domain
• Database Link:
  NP_003780
  Entrez Gene 71609 MouseEntrez Gene 8717 Human
  UniProt ID Q15628
• Background: TRADD Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
• Synonyms: Hs.89862
• Note: TRADD antibody detects endogenous levels of total TRADD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Apoptosis, RIG-I-like receptor signaling pathway