Integrin beta 5 (ITGB5) Rabbit Polyclonal Antibody

CAT#: TA347406

Rabbit Polyclonal Anti-Integrin beta-5 Antibody

Product Images

Western blot analysis on COS7 cell lysate using Integrin beta-5 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Integrin beta-5 Antibody: A synthesized peptide derived from human Integrin beta-5
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 88 kDa
• Gene Name: integrin subunit beta 5
• Database Link:
  NP_002204
  Entrez Gene 16419 MouseEntrez Gene 257645 RatEntrez Gene 3693 Human
  UniProt ID P18084
• Background: ITGB5 Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. Belongs to the integrin beta chain family. Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.
• Synonyms: FLJ26658
• Note: Integrin beta-5 antibody detects endogenous levels of total Integrin beta-5

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton