Bak (BAK1) Rabbit Polyclonal Antibody

CAT#: TA347344

Rabbit Polyclonal Anti-Bak Antibody

Product Images

Western blot analysis on 293 cell lysate using Bak Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Bak Antibody: A synthesized peptide derived from human Bak
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: BCL2 antagonist/killer 1
• Database Link:
  NP_001179
  Entrez Gene 12018 MouseEntrez Gene 578 Human
  UniProt ID Q16611
• Background: Bak1 In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. Belongs to the Bcl-2 family. Interacts with BCL2A1. Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L). Interacts with myxoma virus protein M11L
• Synonyms: BAK; BAK-LIKE; BCL2L7; CDN1
• Note: Bak antibody detects endogenous levels of total Bak

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane