RTF1 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | Western blotting (1:1,000); Immunofluorescence (1:50); Immunoprecipitation (12 µg per IP); ChIP (1 - 5 µg per ChIP) |
Reactivity | Drosophila |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-Rtf1 antibody: drosophila Rtf1 (Rtf1, Paf1/RNA polymerase II complex component, homolog), using the full length recombinant protein. |
Concentration | lot specific |
Purification | In solution in PBS including 0.05% azide and 0.05% ProClin 300. The polyclonal antibody has been protein G purified. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | RTF1 homolog, Paf1/RNA polymerase II complex component |
Database Link | |
Background | PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8. In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control. |
Synonyms | GTL7; KIAA0252 |
Reference Data |
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