MBD3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA (1:100 ?? 1:500); Western blotting (1:2,000) |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-MBD3 antibody: human MBD3 (Methyl-CpG-binding domain protein 3), using three different KLH-conjugated synthetic peptides. |
| Concentration | lot specific |
| Purification | Whole antiserum from rabbit containing 0.05% azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | methyl-CpG binding domain protein 3 |
| Database Link | |
| Background | MBD3 (UniProtKB/Swiss-Prot entry O95983) is a transcriptional repressor which plays a role in gene silencing. Surprisingly, MBD3 does not seem to bind methylated DNA by itself, but acts by the recruitment of histone deacetylases and DNA methyltransferases. MBD3 also forms a heterodimer with MBD2 and is part of the NuRD and the MeCP1 complex. Further, MBD3 interacts with HDAC1, MTA2, DNMT1, p66-alpha and p66-beta. |
| Synonyms | MBD3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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