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KDM1A Rabbit Polyclonal Antibody

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SKU
TA347222
Rabbit Polyclonal LSD1 Antibody
Size:
50 ug
Conjugation:
Unconjugated
  $645.00
5 Days*
Bulk/Customize

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View other "KDM1A or NM_001009999" antibodies

Specifications
Specifications
Product Data
Application ELISA, IF, WB
Recommended Dilution ChIP/ChIP-seq (2-5ug/ChIP); ELISA (1:200 ?? 1:1,000); Western blotting (1:1,000); IF (1:500)
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-LSD1 antibody: human LSD1 (Lysine-specific demethylase 1), using a KLH-conjugated synthetic peptide from the inner part of the protein.
Concentration lot specific
Purification Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name lysine demethylase 1A
Database Link
Background LSD1 (lysine specific demethylase 1, UniProt/Swiss-Prot entry O60341) is a component of the histone demethylase complex that uses FAD as a prosthetic goup. LSD1 may have a dual effect on gene transcription. As it demethylates the mono- and dimethylated 'Lys-4' of histone H3, which are associated with transcriptional activation, LSD1 can act as a repressor of gene expression. However, LSD1 is also capable of demethylating 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to activation of androgen receptor target genes. LSD1 therefore mediates different processes such as embryonic development, cell differentiation and proliferation, stem and cancer cell biology.
Synonyms AOF2; BHC110; CPRF; KDM1; LSD1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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