FKBP51 (FKBP5) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA (1:100 ?? 1:500) ; Western blotting (1:500) |
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-FKBP51 antibody: mouse FKBP51 (FK506 Binding Protein 51), using two KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein |
| Concentration | lot specific |
| Purification | Whole antiserum from rabbit containing 0.05% azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | FK506 binding protein 5 |
| Database Link | |
| Background | FKBP51 (UniProtKB/Swiss-Prot entry Q13451) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It acts as a receptor for FK506 and rapamycin, two immunosuppressants which inhibit T-cell proliferation. FKBP51 is thought to mediate calcineurin inhibition and interacts with progesterone receptor complexes. |
| Synonyms | AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
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