FKBP51 (FKBP5) (NM_004117) Human Recombinant Protein

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SKU
TP310608
Recombinant protein of human FK506 binding protein 5 (FKBP5), transcript variant 1, 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC210608 representing NM_004117
Red=Cloning site Green=Tags(s)

MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS
HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDLKGE
DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQ
REEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFK
GGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN
EKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 51 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004108
Locus ID 2289
UniProt ID Q13451
Cytogenetics 6p21.31
RefSeq Size 3781
RefSeq ORF 1371
Synonyms AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
Summary The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.provided by RefSeq, Mar 2009
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "FKBP51" proteins (10)
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LY429002 Transient overexpression lysate of FK506 binding protein 5 (FKBP5), transcript variant 2 (as WB positive control) 100 ug
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LY429003 Transient overexpression lysate of FK506 binding protein 5 (FKBP5), transcript variant 3 (as WB positive control) 100 ug
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LY429004 Transient overexpression lysate of FK506 binding protein 5 (FKBP5), transcript variant 4 (as WB positive control) 100 ug
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TP760987 Purified recombinant protein of Human FK506 binding protein 5 (FKBP5), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
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