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CTCF Rabbit Polyclonal Antibody

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SKU
TA347107
Rabbit Polyclonal CTCF Antibody
Size:
50 ug
Conjugation:
Unconjugated
  $645.00
5 Days*
Bulk/Customize

Frequently Bought Together (2)

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View other "CTCF or NM_006565" antibodies

Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution ChIP/ChIP-seq (1ug/ChIP); ELISA (1:3,000); Western blotting (1:1,000); Western blotting (1:1,000)
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-CTCF antibody: human CTCF (CCCTC-Binding Factor), using 4 KLH coupled peptides.
Concentration lot specific
Purification Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name CCCTC-binding factor
Database Link
Background CTCF (UniProt/Swiss-Prot entry P49711) is a transcriptional regulator protein with 11 highly conserved zinc finger domains. By using different combinations of the zinc finger domains, CTCF can bind to different DNA sequences and proteins. As such it can act as both a transcriptional repressor and a transcriptional activator. By binding to transcriptional insulator elements, CTCF can also block communication between enhancers and upstream promoters, thereby regulating imprinted gene expression. CTCF also binds to the H19 imprinting control region and mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Mutations in the CTCF gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumor.
Synonyms MRD21
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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