BAZ2A Rabbit Polyclonal Antibody

SKU
TA347082
Rabbit Polyclonal TIP-5 Antibody
  $645.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution ChIP (5 µl/ChIP); Western blotting (1:1,000)
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-TIP-5 antibody: TIP5 (Transcription termination factor I-interacting protein 5), using the recombinant protein.
Concentration lot specific
Purification Whole antiserum from rabbit containing 0.05% azide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name bromodomain adjacent to zinc finger domain 2A
Database Link
Background TIP 5 (UniProt/Swiss-Prot entry Q9UIF9) is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
Synonyms TIP5; WALp3
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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