BAZ2A Rabbit Polyclonal Antibody

SKU TA347082

Rabbit Polyclonal TIP-5 Antibody

Product Data

• Application: WB
• Recommended Dilution: ChIP (5 µl/ChIP); Western blotting (1:1,000)
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TIP-5 antibody: TIP5 (Transcription termination factor I-interacting protein 5), using the recombinant protein.
• Concentration: lot specific
• Purification: Whole antiserum from rabbit containing 0.05% azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: bromodomain adjacent to zinc finger domain 2A
• Database Link:
  NP_038477
  Q9UIF9
• Background: TIP 5 (UniProt/Swiss-Prot entry Q9UIF9) is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
• Synonyms: TIP5; WALp3

Reference Data

• Protein Families: Druggable Genome