Loricrin (LOR) Rabbit Polyclonal Antibody

CAT#: TA346191

Rabbit Polyclonal Anti-LOR Antibody

Product Images

WB Suggested Anti-LOR Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate

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  Rabbit Anti-LOR Antibody; Paraffin Embedded Tissue: Human Kidney; Cellular Data: Epithelial cells of renal tubule; Antibody Concentration: 4.0-8.0 ug/ml; Magnification: 400X

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-LOR antibody: synthetic peptide directed towards the N terminal of human LOR. Synthetic peptide located within the following region: GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: loricrin
• Database Link:
  NP_000418
  Entrez Gene 4014 Human
  UniProt ID P23490
• Background: LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
• Synonyms: MGC111513
• Note: Immunogen Sequence Homology: Human: 100%; Bovine: 93%; Mouse: 86%; Pig: 75%; Guinea pig: 75%

Reference Data

• Protein Families: Druggable Genome