EIF2A Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB, IHC |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-EIF2A antibody: synthetic peptide directed towards the C terminal of human EIF2A. Synthetic peptide located within the following region: DKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQLKEQ |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Purification | Protein A purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 64 kDa |
| Gene Name | eukaryotic translation initiation factor 2A |
| Database Link | |
| Background | EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002). supplied by OMIM |
| Synonyms | CDA02; EIF-2A; MST089; MSTP004; MSTP089 |
| Note | Immunogen Sequence Homology: Dog: 100%; Rat: 100%; Human: 100%; Pig: 93%; Mouse: 93%; Rabbit: 93%; Zebrafish: 93%; Guinea pig: 93%; Horse: 86%; Bovine: 86%; Goat: 83% |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
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Citations
Predisposition to cortical neurodegenerative changes in brains of hypertension prone rats
Ben-Shabat, Awad-Igbaria, Sela et al
J Transl Med (2023) 21 (1), 51 DOI: 10.1186/s12967-023-03916-y
Ben-Shabat, Awad-Igbaria, Sela et al
J Transl Med (2023) 21 (1), 51 DOI: 10.1186/s12967-023-03916-y
Cited by 14
AI Summary: In this study, the OriGene product anti-eIF2α ~ P antibody (TA343946) was used for immunofluorescence staining to assess stress response protein expression in rat brain cortical tissues, contributing to the investigation of molecular mechanisms underlying neurodegeneration associated with hypertension.
Snippet: , Novus Biologicals);cleaved anti-Caspase-3 (1:100;#CPP324, Zytomed System);Anti HDAC2 (1:250;#Y461, Millipore);anti-HAT1 (1:250;#11432, Proteintech Group);anti-eIF2α ~ P (1:200;TA343946 OriGene Inc.) Slides were rinsed 3 times using wash buffer and incubated for 1 h with a secondary antibody anti-rabbit/mice 594 (1:150;Bethyl Laboratories, Inc.), followed by three cycles of wash bu
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