GFM2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-GFM2 antibody: synthetic peptide directed towards the C terminal of human GFM2. Synthetic peptide located within the following region: TVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVE |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 86 kDa |
| Gene Name | G elongation factor, mitochondrial 2 |
| Database Link | |
| Background | Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. |
| Synonyms | EF-G2mt; EFG2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt |
| Note | Immunogen Sequence Homology: Human: 100%; Dog: 93%; Pig: 86%; Horse: 86%; Bovine: 79% |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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