The immunogen for anti-FOXH1 antibody: synthetic peptide directed towards the middle region of mouse FOXH1. Synthetic peptide located within the following region: GPSSSSETPLWPLCSLPGPTIIEGESSQGEVIRPSPVTPDQGSWPLHLLE
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Foxh1 is a transcriptional activator. Foxh1 can recognizes and binds toThe DNA sequence 5'-TGTGTGTATT-3' and is required for induction ofThe goosecoid (GSC) promoter by TGF-beta or activin signaling. Foxh1 forms a transcriptionally active complex containing FAST-1/SMAD2/SMAD4 on a site onThe GSC promoter called TARE (TGF-beta/activin response element).
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