CLK1 Rabbit Polyclonal Antibody

CAT#: TA340041

Rabbit Polyclonal Anti-CLK1 Antibody

Product Images

Sample type: human microvascular endothelial cells (25ug); Primary Dilution: 1: 1000; Secondary Antibody: Goat anti-Rabbit-HRP; Secondary Dilution: 1: 5000; Image Submitted by: Andreas Eisenreich; Charite Universitatsmedizin Berlin

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  WB Suggested Anti-CLK1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysateCLK1 is supported by BioGPS gene expression data to be expressed in HEK293T

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-CLK1 antibody: synthetic peptide directed towards the N terminal of human CLK1. Synthetic peptide located within the following region: HSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGC
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: CDC like kinase 1
• Database Link:
  NP_004062
  Entrez Gene 1195 Human
  UniProt ID P49759
• Background: This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CLK; STY
• Note: Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Horse: 100%; Human: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Mouse: 86%; Rat: 85%

Reference Data

• Protein Families: Druggable Genome, Protein Kinase