GSDME Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB, IHC |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-DFNA5 antibody: synthetic peptide directed towards the C terminal of human DFNA5. Synthetic peptide located within the following region: AALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQR |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | lot specific |
| Purification | Protein A purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 47 kDa |
| Gene Name | DFNA5, deafness associated tumor suppressor |
| Database Link | |
| Background | Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Synonyms | ICERE-1 |
| Note | Immunogen Sequence Homology: Human: 100%; Rat: 85%; Bovine: 85%; Pig: 83%; Guinea pig: 83%; Dog: 77% |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Caspase-3 and gasdermin E detection in peri-implantitis
Chen, Jiang, Jiang et al
Biochim Biophys Acta Mol Basis Dis (2021) 1867 (11), 166217 DOI: 10.1016/j.bbadis.2021.166217
Chen, Jiang, Jiang et al
Biochim Biophys Acta Mol Basis Dis (2021) 1867 (11), 166217 DOI: 10.1016/j.bbadis.2021.166217
Cited by 20
AI Summary: OriGene's GSDME rabbit polyclonal antibody (TA339270) was used for immunohistochemical staining to detect GSDME expression in peri-implantitis tissue samples in this study.
Snippet: IHC staining was performed using the following antibodies: GSDME rabbit polyclonal antibody (TA339270, 1:500, Origene, USA) and anti-caspase-3 antibody (ab195905, 1:100, Abcam, USA). Images were randomly captured under a microscope (Leika, Germany)
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