BST2 Rabbit Polyclonal Antibody

SKU TA337141

Rabbit Polyclonal BST2 Antibody

Product Data

• Application: FC, IHC, Simple Western, WB
• Recommended Dilution: Immunohistochemistry, Western Blot: 2 - 4 ug/mL, Immunohistochemistry-Paraffin: 5 ug/mL, Immunofluorescence, Simple Western: 1:200, Flow Cytometry, Flow (Cell Surface), Immunohistochemistry-Frozen
• Reactivity: Human, Mouse, Primate, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A portion of amino acids 80-130 of human BST2 was used as the immunogen for this antibody.
• Buffer: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: bone marrow stromal cell antigen 2
• Database Link:
  NP_004326
  Q10589
• Background: BST2, also known as CD317, HM1.24 antigen, DAMP-2 and recently designated tetherin, is an integral membrane protein with a novel topology. The specific function of the BST2, encoded by the bone marrow stromal cell antigen 2 gene, is undetermined; however, it may play a role in pre-B-cell growth, rheumatoid arthritis, and in antiretroviral defense, that blocks release of retrovirus from the cell surface. BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, Nk cells and DCs (at protein level).
• Synonyms: CD317; TETHERIN
• Note: BST2 is a 180 amino acid protein with an observed molecular weight of approximately 30 kDa in western blotting (see Ishikawa et all, 1995 PMID 7607676). FLOW application of this product is reported by Crother et al 2011 PMID 21695198.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane