HEY1 Rabbit Polyclonal Antibody

SKU
TA337140
Rabbit Polyclonal HEY1 Antibody
  $575.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution Western Blot: 2-4ug/ml
Reactivity Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen A portion of amino acids 50-100 of mouse Hey1 was used as the immunogen.
Buffer PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein A purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name hes related family bHLH transcription factor with YRPW motif 1
Database Link
Background Hairy/enhancer-of-split related with YRPW motif protein 1 belongs to the HEY family and is a Notch Signaling Pathway Protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It acts as transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. It represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Hey1 is also reported to be expressed during development of the nervous system.
Synonyms BHLHb31; CHF2; HERP2; HESR1; hHRT1; HRT-1; OAF1
Note This antibody has been tested in Western blot on mouse tissue. The Western blot results on human tissue have been mixed.
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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