EBI3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 2-6 ug/ml |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | A portion of amino acids 50-100 of human EBI3 was used as the immunogen. |
| Buffer | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Concentration | lot specific |
| Purification | Protein G purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | Epstein-Barr virus induced 3 |
| Database Link | |
| Background | EBI3 is a novel hematopoietin receptor family member related to the p40 subunit of interleukin-12 and to the ciliary neurotrophic factor receptor. It's expression is induced in B lymphocytes by Epstein-Barr virus (EBV) infection. Human EBI3 gene maps to chromosome 19p13.3, near genes encoding the erythropoietin receptor and the cytokine receptor-associated kinase, Tyk2. The protein is expressed in vivo by scattered cells in interfollicular zones of tonsil tissue, by cells associated with sinusoids in perifollicular areas of spleen tissue, and at very high levels by placental syncytiotrophoblasts. EBI3 expression in vitro is induced in EBV-negative cell lines by expression of the EBV latent infection membrane protein-1 and in peripheral blood mononuclear cells by pokeweed mitogen stimulation. The protein plays a crucial role in regulating cell-mediated immune responses. |
| Synonyms | IL-27B; IL27B |
| Reference Data | |
| Protein Categories | Cytokines, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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